MEF2A monoclonal antibody (M03), clone 1D11
产品名称: MEF2A monoclonal antibody (M03), clone 1D11
英文名称: MEF2A monoclonal antibody (M03), clone 1D11
产品编号: H00004205-M03
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: 2023-09-20T22:28:01
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant MEF2A.
- Immunogen:
- MEF2A (AAH13437, 71 a.a. ~ 170 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- EYNEPHESRTNSDIVEALNKKEHRGCDSPDPDTSYVLTPHTEEKYKKINEEFDNMMRNHKIAPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAA
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2b Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37 KDa) .
- MSDS:
- Download
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge this image
- Immunoperoxidase of monoclonal antibody to MEF2A on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged MEF2A is approximately 0.3ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 4205
- GeneBank Accession#:
- BC013437
- Protein Accession#:
- AAH13437
- Gene Name:
- MEF2A
- Gene Alias:
- ADCAD1,RSRFC4,RSRFC9
- Gene Description:
- myocyte enhancer factor 2A
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.[supplied by OMIM
- Other Designations:
- MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A)
- Related Disease
- Atherosclerosis
- Cardiomyopathy, Hypertrophic
- Cardiovascular Diseases
- Coronary Artery Disease
- Diabetes Mellitus
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Hypertension
- Hypertrophy, Left Ventricular
- Insulin Resistance
- Myocardial Infarction
- Myocardial Ischemia
- Polycystic Ovary Syndrome
- Tobacco Use Disorder