FITC标记的轴突导向因子SEMA3E抗体
产品名称： FITC标记的轴突导向因子SEMA3E抗体
英文名称： Anti-Semaphorin 3E/FITC
产品编号： HZ-11480R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Semaphorin 3E/FITC Conjugated antibody
FITC标记的轴突导向因子SEMA3E抗体
| 产品编号 | bs-11480R-FITC |
| 英文名称 | Anti-Semaphorin 3E/FITC |
| 中文名称 | FITC标记的轴突导向因子SEMA3E抗体 |
| 别 名 | Coll 5; Coll5; KIAA0331; M sema H; M SEMAH; M SemaK; Msema H; MSEMAH; MSemaK; SEM3E_HUMAN; Sema domain immunoglobulin domain (Ig); Sema domain immunoglobulin domain (Ig) short basic domain secreted 3E; Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; SEMA3E; SEMAH; Semaphorin 3E; Semaphorin-3E; Semaphorin3E; Short basic domain secreted (semaphorin) 3E; SEM3E_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 细胞膜蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 86kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SEMA3E/Semaphorin 3E (401-450aa) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. This gene encodes a class 3 semaphorin. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010] Function: Plays an important role in signaling via the cell surface receptor PLXND1. Mediates reorganization of the actin cytoskeleton, leading to the retraction of cell projections. Promotes focal adhesion disassembly and inhibits adhesion of endothelial cells to the extracellular matrix. Regulates angiogenesis, both during embryogenesis and after birth. Can down-regulate sprouting angiogenesis. Required for normal vascular patterning during embryogenesis. Plays an important role in ensuring the specificity of synapse formation Subunit: Interacts with PLXND1 Subcellular Location: Secreted. Similarity: Belongs to the semaphorin family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Sema domain. Database links: Entrez Gene: 9723 Human Entrez Gene: 20349 Mouse Entrez Gene: 100524100 Pig Entrez Gene: 296789 Rat Entrez Gene: 535644 Cow Entrez Gene: 483387 Dog Omim: 608166 Human SwissProt: O15041 Human SwissProt: P70275 Mouse SwissProt: Q9QX23 Mouse Unigene: 528721 Human Unigene: 134093 Mouse Unigene: 214084 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
SimaPrrin是一个保守的分泌和膜相关蛋白家族，在N-末端细胞外部分具有信号素（SEMA）结构域和PSI结构域（在丛蛋白、信号素和整合素中发现）。根据序列和结构相似性，SimaPrin被分为八类：无脊椎动物包含1类和2类，病毒具有V类，脊椎动物包含3-7类。SimaPrin通过多聚体受体复合物作为轴突导向配体，一些（如果不是全部）含有丛蛋白。该基因编码4类信号素。该基因编码3类信号素。该基因已发现编码不同亚型的多个转录变体。